New Science New Tests

There is a new scientific understanding of the arterial disease behind heart attack and stroke. New tests enable the Center for Prevention Heart Attack and Stroke to provide more individualized and effective treatments.  Here are a few of the tests:

  • Carotid Intima Media Thickness testing (CIMT). CIMT measures arterial wall thickness. A thick artery is a sick artery. This is more important than “blockage” in predicting new unstable plaque formation. Unstable plaque causes heart attacks and strokes. Proactive Optimal Care can reverse arterial disease and make arteries healthier.

  • LpPLA2, also known as the PLAC test, rises when arteries are inflamed or “hot.” You want your arteries to be “cool.” Myeloperoxidase (MPO) rise should trigger a search for inflammation, especially from the mouth. Other tests for inflammation like hs CRP and Microalbumin/Creatinine ratio can guide and monitor the effectiveness of therapy.

  • Genetic testing can inform you of your risk and motivate change in lifestyle and preventive treatment. It can also guide the choice of the most effective and safe medication and diet. The earlier these results are known, the more beneficial and cost effective because their one time cost can be amortized over a longer lifetime.

  • Haptoglobin genotype (Hp) determines if Vitamin E offers powerful protection (Hp2-2) or increases risk (Hp 1-1 and 1-2). This is the most powerful example of Personalized or Precision Medicine we offer.

  • Testing for insulin resistance (prediabetes) is important to identify those who could be developing vascular complications well before they are diagnosed with Type 2 Diabetes. Visceral Fat Level, measured on the InBody 570, provides detection and monitoring of insulin resistance response to changes in what and when we eat.

  • Coronary Calcium Score (CACS) detects mature calcified plaque in coronary arteries, but can miss new plaque. It is not useful in monitoring therapy benefit. It is recommended in a more limited role where CIMT does not reveal plaque but there is still suspicion of coronary artery disease.

  • Home Sleep Testing and automated CPAP have made the diagnosis and management of Sleep Apnea more affordable and effective. Sleep Apnea is a root cause for heart attack and stroke. Treating it can lower your risk of heart attack and stroke.

  • Oral DNA (MyPeriopath) testing can determine if you have certain bacteria in the mouth that are associated with a higher risk of arterial inflammation. In some cases, this can have a significant effect on management of periodontal inflammation which contributes to heart attack and stroke risk.

  • Personalized Genomic Testing offers insight into risk of disease and individual differences in drub metabolism, benefit and risk. This is especially valuable for those taking multiple medications and supplements that can interact, causing potential for harm. An interactive website allows predictive modeling of the effect of changes in therapy.